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. 2024 Dec 27;19(12):e0309178. doi: 10.1371/journal.pone.0309178

Fig 3. The amount of cfDNA and their fragment size by stage or distant metastasis.

Fig 3

A-1 and A-2: The amount of stage III/IV cfDNA is significantly higher than that of stage I/II cfDNA in preoperative conditions, but not significant in postoperative conditions. B-1 and B-2: The amount of cfDNA in patients with distant metastatic cases is significantly higher than that in patients without distant metastasis both preoperatively and postoperatively. C-1 and C-2: No significant differences are observed between the size of cfDNA in stage I/II or stage III/IV cancers, both preoperatively and postoperatively. D-1 and D-2: The size of cfDNA in distant metastatic cases was significantly shorter than that in in non-distant metastatic cases preoperatively, but not postoperatively.