Figure 2.

Reducing protein or non-essential amino acids in diet induces significant changes in the levels of metabolites in the liver, serum and feces. Small molecules that were significantly changed (p adj < 0.05) in abundance in the livers (A), serum (B), feces (C) or all three matrices combined (D) from mice fed a reduced protein (RP) or reduced NEAA (RN) diet compared to mice given a control diet (CL) are shown as heat maps. Red color indicates increased abundance; blue color indicates decreased abundance.