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. 2024 Dec 18;13(24):7726. doi: 10.3390/jcm13247726

Table 3.

Linear regression analysis of supine, end-tilt, and change in HR, SVI, and CI data in patients with postural orthostatic tachycardia syndrome, in patients with a normal HR-BP response during the tilt, and in healthy controls with a normal heart rate and blood pressure during the tilt.

Group SVI (Y) vs. HR (x) * Linear Regression Line R2 p-Value
Group 1, ME/CFS with POTS SVI supine Y = −0.185x + 5028 0.157 p < 0.001
SVI end-tilt Y = 0.005x + 18.6 0.000 p = 0.784
Delta SVI Y = 0.092x − 21.6 0.036 p = 0.004
Group 2, ME/CFS with normal HR-BP response SVI supine Y = −0.220x + 52.9 0.159 p < 0.001
SVI end-tilt Y = −0.154x + 35.9 0.192 p < 0.001
Delta SVI Y = −0.308x −10.1 0.273 p < 0.001
Group 3, healthy controls SVI supine Y = −0.284x + 54.8 0.253 p < 0.001
SVI end-tilt Y = −0.232x + 45.3 0.390 p < 0.001
Delta SVI Y = −0.273x − 5.6 0.368 p < 0.001

BP: blood pressure; HR: heart rate; POTS: postural orthostatic tachycardia syndrome; SVI: stroke volume index. ME/CFS: myalgic encephalomyelitis/chronic fatigue syndrome; *: supine or end-tilt, or changes (delta: end-tilt minus supine) in parameters, where appropriate.