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. 2024 Dec 18;13(24):7726. doi: 10.3390/jcm13247726

Table 4.

Hemodynamic results of ME/CFS patients with postural orthostatic tachycardia syndrome (POTS) with a heart rate increase of 30–39 bpm and ME/CFS patients with POTS with a heart rate increase ≥40 bpm.

Group 2 POTS with HR Increase of 30–39 bpm at End-Tilt (n= 145) Group 3 POTS with HR Increase of ≥40 bpm at End-Tilt (n = 88) t Test/Mann–Whitney U Test: p-Value
supine HR (bpm) 74 (12) 75 (12) p = 0.48
end-tilt HR (bpm) 105 (98–114) 121 (113–132) p < 0.001
delta HR (bpm) 33 (3) 48 (7) p < 0.001
supine SVI (mL/m2) 38 (5) 36 (7) p = 0.119
end-tilt SVI (mL/m2) 18 (17–20) 20 (17–23) p = 0.005
delta SVI (mL/m2) −19 (4) −16 (5) p < 0.001
supine CI (L/min/m2) 2.75 (0.49) 2.69 (0.48) p = 0.366
end-tilt CI (L/min/m2) 1.93 (1.71–2.17) 2.53 (2.21–2.90) p < 0.001
delta CI (L/min/m 2) −0.77 (0.24) −0.12 (0.28) p < 0.001
supine SBP (mmHg) 132 (15) 133 (15) p = 0.647
end-tilt SBP (mmHg) 128 (18) 127 (19) p = 0.874
supine DBP (mmHg) 80 (11) 80 (8) p = 0.672
end-tilt DBP (mmHg) 89 (14) 87 (13) p = 0.314

SBP: systolic blood pressure; DBP: diastolic blood pressure HR: heart rate; POTS: postural orthostatic tachycardia syndrome; SVI: stroke volume index. CI: cardiac index.

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