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. 2024 Dec 11;16(12):1584. doi: 10.3390/pharmaceutics16121584

Table 6.

Inhaled antineoplastics evaluated in clinics.

Drug Dose Cancer Type Reference
Gemcitabine 1–4 mg/kg NSCLC [186]
Doxorrubicin 0.4–9.4 mg/m2 Primary and metastases in the lungs [187]
5-Fluorouracil 250 mg NSCLC [188]
Carboplatin (iv or inhaled) +Docetaxel (iv) Docetaxel: 100 mg/m2
Carboplatin: AUC 5.5
NSCLC [189]
Liposomal cisplatin 1.5–48 mg/m2 NSCLC [190]
Liposomal 9-Nitrocamptothecin 6.7–26.6 µg/kg/day Primary lung cancer
Metastases in the lungs
[191]

Key: non-small cell lung cancer (NSCLC); intravenous (iv); area under the curve (AUC).