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. 2024 Dec 16;25(24):13482. doi: 10.3390/ijms252413482

Table 1.

Three drugs against the SARS-CoV-2 3CL protease and their detailed information.

Drug Name Common Name Design Team FDA Approved Clinical Trials PubChem CID
Nirmatrelvir Paxlovid Pfizer Yes Yes 155903259
Bofutrelvir FB2001 Shanghai Institute of Materia Medica, Chinese Academy of Sciences; Wuhan Branch, Chinese Academy of Sciences; Frontier Biotechnologies, Inc. (China) No Yes 145343771
Selinexor KPT-330 Karyopharm Therapeutics Yes Yes 71481097