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. 2024 Dec 16;16(12):546. doi: 10.3390/toxins16120546

Table 1.

Demographics, clinical characteristics, and results of BoNT therapy.

Age (years) [mean ± SD] 54.5 ± 9.1
Sex, (n [%]) Women
Men
NR
669 (60.3)
413 (37.4)
21 (1.9)
Etiology, (n [%]) Idiopathic
Tardive
Acquired
NR
650 (58.9)
272 (24.7)
138 (12.5)
72 (6.5)
Subtype of OMD, (n [%]) Jaw closing dystonia
Tongue dystonia
Jaw opening dystonia
Mixed dystonia
Jaw deviation dystonia
Jaw protrusion dystonia
Lip dystonia
Perioral dystonia
NR
438 (39.7)
252 (22.8)
193 (17.5)
74 (6.7)
46 (4.2)
18 (1.6)
13 (1.2)
1 (0.1)
88 (8)
Other dystonia, (n [%]) Cervical dystonia
Blepharospasm
Limb dystonia
Spasmodic dysphonia
Writer‘s cramp
Generalized dystonia
Embouchure dystonia
Other
NR
181 (16.4)
153 (13.9)
43 (3.9)
27 (2.4)
15 (1.4)
10 (0.9)
3 (0.3)
2 (0.2)
208 (18.9)
Number of injections (times) [mean ± SD] 4.1 ± 2.8
Muscles injected, (n [%]) Masseter
Lateral pterygoid
Genioglossus
Temporalis
Submentalis
Medial pterygoid
Anterior digastric
Posterior digastric
Orbicularis oris
Risorius
Mentalis
Platysma
Sternocleidomastoid
Other
NR
537 (48.7)
278 (25.2)
258 (23.4)
210 (19)
186 (16.9)
60 (5.4)
47 (4.3)
30 (2.7)
29 (2.6)
17 (1.5)
15 (1.4)
14 (1.3)
12 (1.1)
46 (4.2)
31 (2.8)
Dose (units) [mean ± SD] Masseter
Lateral pterygoid
Genioglossus
Temporalis
Submentalis
Medial pterygoid
Anterior digastric
Posterior digastric
Platysma
43.8 (35.7)
37.1 (48.9)
22.2 (12.6)
26.2 (14.3)
23.8 (9.2)
19 (5.7)
17.1 (7.9)
8.9 (4.6)
12.3 (6.7)
Adverse events, (n [%]) Dysphagia
Dysarthria
Pain
Chewing difficulty
Lip numbness
Swelling
None
Other
111 (10.1)
10 (0.9)
9 (0.8)
5 (0.5)
5 (0.5)
2 (0.2)
881 (79.9)
37 (3.4)

OMD, oromandibular dystonia; NR, not reported.