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. 2024 Dec 7;22(12):552. doi: 10.3390/md22120552

Table 5.

Collated bioactivity results for Saponins 1–3, elucidated from a C. novaguineae isolation [7].

Saponin Structure Cell Line Measure Concentration (µM)
Saponin 1
(C55H89NaO27S)
graphic file with name marinedrugs-22-00552-i017.jpg Erythrocyte ED50 12.79 *
Pyricularia oryzae MMDC 6.39 *
K-562 (1) IC50 2.85 *
BEL-7402 (2) IC50 2.04 *
Saponin 2
(C49H77NaO26S)
graphic file with name marinedrugs-22-00552-i018.jpg Erythrocyte ED50 >34.75 *
Pyricularia oryzae MMDC 222.38 *
K-562 (1) IC50 >43.4 *
BEL-7402 (2) IC50 >43.4 *
Saponin 3
(C56H91NaO27S)
graphic file with name marinedrugs-22-00552-i019.jpg Erythrocyte ED50 24.50 *
Pyricularia oryzae MMDC 3.16 *
K-562 (1) IC50 2.96 *
BEL-7402 (2) IC50 1.49 *

* Note: converted units from µg/mL. (1) Method: MTT colorimetric assay, 48 h incubation. (2) Method: SRB colorimetric assay, 48 h incubation.