Table 3.

Associations between maternal SARS-CoV-2 infection and at receipt of at least one maternal SARS-CoV-2 vaccination and selected outcomes. Significant adjusted RR for SARS-CoV-2 infection and SARS-CoV-2 vaccination are shown.

Outcome	Unadjusted RR (95% CI) Exposure: SARS-CoV-2 Infection	Adjusted RR (95% CI) Exposure: SARS-CoV-2 Infection	Unadjusted RR (95% CI) Exposure: At Least One COVID-19 Vaccine Dose	Adjusted RR (95% CI) Exposure: At Least One COVID-19 Vaccine Dose
Hypertensive disorders in pregnancy	0.87 (0.73–1.05)		1.19 (0.99–1.42)
Postpartum hemorrhage	0.93 (0.73–1.19)		0.77 (0.57–1.05)
Maternal sepsis	0.91 (0.59–1.40)		0.17 (0.46–0.66)	0.14 (0.03–0.56)
Preterm birth	1.09 (0.91–1.31)		1.31 (1.04–1.66)
Fetal demise	1.21 (0.91–1.60)		0.77 (0.49–1.21)
ICU admission	1.34 (1.05–1.70)		0.28 (0.12–0.64)	0.27 (0.10–0.68)
Maternal Ventilator support	1.23 (1.06–1.49)	1.48 (1.08–2.03)	0.62 (0.47–0.82)	0.60 (0.43–0.84)
Birthweight (SGA or LGA)	0.93 (0.75–1.14)		0.83 (0.65–1.06)
NICU-admission (n = 520)	1.22 (1.03–1.45)		0.65 (0.52–0.82)	0.62 (0.47–0.82)
Neonatal Respiratory Distress (n = 520)	1.05 (0.87–1.27)		0.65 (0.51–0.85)	0.60 (0.43–0.83)

SARS-CoV-2 vaccination was defined as having at least 1 dose of vaccine administered prior to hospitalization. Each outcome of interest was analyzed in individual multivariate models, controlling for age, parity, gestational age, preexisting comorbidities, as well as the exposures of interest (i.e., SARS-CoV-2 infection and COVID-19 vaccination). Adjusted RRs for SARS-CoV-2 infection and COVID-19 vaccination are derived from each of the models.