Fig. 5.

Effect of paclitaxel (PTX) and rosiglitazone (RGZ) on the mitochondrial membrane potential in SKOV-3 ovarian cancer cells. (a) Mitochondria were stained by JC-1 fluorescent dye. Red-colored mitochondria have their membrane polarized while green stain represents unpolarized mitochondria. (b) Percent ratio of red versus green fluorescence in SKOV-3 ovarian cancer cells. Error bars represent the mean ± SEM of three independent experiments. ***< 0.001 as compared to that of the control. ^###< 0.001 as compared to that of the PTX alone. ^@@@< 0.001 as compared to that of the RGZ alone.