Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Dec 28;14:30663. doi: 10.1038/s41598-024-75251-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — Identification of differentially expressed genes in CTEPH by limma and WGCNA packages. (A) PCA diagram of the DEGs expression. Red represents gene up-regulation and blue represents gene down-regulation. (B) Scale independence diagram. (C) Average connectivity graph. The soft threshold is 22. (D) Hierarchical clustering tree of MRNA expression patterns of 18 samples. Sample aggregation, no outlier samples. (E) Correlation diagram between modules. (F) Dendrogram of all differentially expressed genes clustered based on different similarity measures. Turquoise, gray, blue and brown are the four modules with the highest degree of clustering. (G) Heat map of the characteristic genes of the module. (H) Scatterplot of correlation between modules and clinical traits. Gray (r = 0.78, p = 1.5e−61), blue (r = 0.63, p = 2.7e−17). (I) Intersection gene map of limma package and WGCNA package.