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. 2024 Nov 19;27(12):111429. doi: 10.1016/j.isci.2024.111429

Figure 2.

Figure 2

Fly-through of coronal slices in the brain highlighting the voxel-wise significant differences in absolute and relative volume between housing conditions

Left: differences between altered Schaedler flora (ASF) and specific pathogen-free (SPF) mice, middle: differences between germ-free (GF) and SPF mice, right: differences between conventionalized GF (GFSPF) and SPF mice. Orange/red highlighted regions were significantly larger in SPF mice compared to GF mice and blue highlighted regions were significantly smaller in SPF mice. For GF F, n = 13; GF M, n = 10; SPF F, n = 15; SPF M, n = 15; GFSPF F, n = 11; GFSPF M, n = 12; ASF F, n = 6; ASF M, n = 6. All changes highlighted were significant at an FDR value of < 0.05.