Table 1.
Baseline characteristics of participants.
| Variables | ALL patients | Unintentional Weight Loss | P value | |
|---|---|---|---|---|
| (n = 1842) | No (n = 1585) | Yes (n = 257) | ||
| Age(years) | 66.2 ± 17.5 | 66.3 ± 17.6 | 65.6 ± 17.1 | 0.537 |
| Gender, n(%) | 0.037 | |||
| Female | 842 (45.7) | 740 (46.7) | 102 (39.7) | |
| Male | 1000 (54.3) | 845 (53.3) | 155 (60.3) | |
| Race/Ethnicity,n(%) | 0.551 | |||
| White | 1312 (71.2) | 1131 (71.4) | 181 (70.4) | |
| African Americans | 135 (7.3) | 112 (7.1) | 23 (8.9) | |
| Other | 395 (21.4) | 342 (21.6) | 53 (20.6) | |
| Insurance,n (%) | 0.13 | |||
| Medicare | 898 (48.8) | 787 (49.7) | 111 (43.2) | |
| Medicaid | 138 (7.5) | 119 (7.5) | 19 (7.4) | |
| Other | 806 (43.8) | 679 (42.8) | 127 (49.4) | |
| Weight(kg) | < 0.001 | |||
| < 50 | 63 (3.5) | 36 (2.3) | 27 (10.6) | |
| 50–100 | 1342 (73.8) | 1143 (73.1) | 199 (78) | |
| > 100 | 413 (22.7) | 384 (24.6) | 29 (11.4) | |
| Laboratory metries | ||||
| Heart rate(bpm) | 91.1 ± 16.9 | 91.0 ± 16.6 | 91.8 ± 18.7 | 0.506 |
| MAP(mmHg) | 77.3 ± 10.2 | 77.4 ± 10.1 | 76.6 ± 11.0 | 0.252 |
| WBC(× 109/L) | 15.4 (10.3, 21.8) | 15.5 (10.6, 21.9) | 15.1 (9.0, 21.4) | 0.183 |
| Glucose(mmol/L) | 7.9 ± 3.0 | 7.9 ± 3.0 | 7.6 ± 2.7 | 0.148 |
| Hb(g/L) | 9.9 ± 2.0 | 10.1 ± 2.0 | 9.0 ± 1.9 | < 0.001 |
| Alb(g/L) | < 0.001 | |||
| < 30 | 602 (32.7) | 482 (30.4) | 120 (46.7) | |
| ≥ 30 | 580 (31.5) | 520 (32.8) | 60 (23.3) | |
| NA* | 660 (35.8) | 583 (36.8) | 77 (30) | |
| Scr(mg/dL) | 1.4 (1.0, 2.4) | 1.4 (1.0, 2.4) | 1.3 (0.9, 2.2) | 0.016 |
| TBIL(mg/dL) | 1.4 (0.6, 2.7) | 1.5 (0.6, 2.7) | 1.1 (0.5, 2.7) | 0.009 |
| CCI | 5.0 (4.0, 7.0) | 5.0 (4.0, 7.0) | 6.0 (4.0, 8.0) | 0.581 |
| APSIII | 60.6 ± 25.4 | 60.2 ± 25.4 | 63.1 ± 25.5 | 0.091 |
| SOFA | 3.8 ± 2.0 | 3.8 ± 2.0 | 3.6 ± 1.6 | 0.071 |
| 30-Day Mortality,n(%) | < 0.001 | |||
| No | 1488 (80.8) | 1303 (82.2) | 185 (72) | |
| Yes | 354 (19.2) | 282 (17.8) | 72 (28) | |
| Septic Shock | 0.273 | |||
| No | 1349 (73.2) | 1168 (73.7) | 181 (70.4) | |
| Yes | 493 (26.8) | 417 (26.3) | 76 (29.6) | |
| Source of Sepsis | 0.026 | |||
| Urinary Tract | 347 (18.8) | 310 (19.6) | 37 (14.4) | |
| Lungs | 300 (16.3) | 254 (16) | 46 (17.9) | |
| Gastrointestinal Tract | 113 (6.1) | 91 (5.7) | 22 (8.6) | |
| Others | 136 (7.4) | 125 (7.9) | 11 (4.3) | |
| NA* | 946 (51.4) | 805 (50.8) | 141 (54.9) | |
| Pathogens Causing Sepsis | 0.082 | |||
| Escherichia Coli | 114 (6.2) | 107 (6.8) | 7 (2.7) | |
| Streptococcus | 93 (5.0) | 77 (4.9) | 16 (6.2) | |
| Clostridium Difficile | 61 (3.3) | 49 (3.1) | 12 (4.7) | |
| Staphylococcus Aureus | 96 (5.2) | 86 (5.4) | 10 (3.9) | |
| Others | 47 (2.6) | 39 (2.5) | 8 (3.1) | |
| NA* | 1431 (77.7) | 1227 (77.4) | 204 (79.4) | |
Continuous variables are presented as the mean ± SD or median (quartile), while categorical variables are presented as absolute numbers (percentages).
MBP, mean blood pressure; WBC, white blood cell; Hb, hemoglobin; Alb, albumin; NA*, missing values; Scr, serum creatinine; TBIL, total bilirubin; CCI, Charlson comorbidity index; APSIII, acute physiology score III; SOFA, sequential organ failure assessment.