Table 1.
Characteristics of the study population.
| Male (n = 1,756) | |||||
|---|---|---|---|---|---|
| UHR (%) | Q1(8.79–23.53) | Q2(23.56–28.79) | Q3(28.80–35.50) | Q4(35.52–59.55) | P value |
| Age (years) | 54.69 ± 11.68 | 51.95 ± 11.81 | 50.32 ± 11.74 | 48.06 ± 12.64 | < 0.001 |
| Nationality (%) | 0.107 | ||||
| non-Han nationality | 2(0.46%) | 1(0.23%) | 5(1.13%) | 7(1.59%) | |
| Han nationality | 434(99.54%) | 439(99.77%) | 436(98.87%) | 432(98.41%) | |
| Marital status (%) | 0.232 | ||||
| Not married | 17(3.90%) | 15(3.41%) | 24(5.44%) | 26(5.92%) | |
| Married | 419(96.10%) | 425(96.59%) | 417(94.56%) | 413(94.08%) | |
| BMI (kg/m2), (%) | < 0.001 | ||||
| < 24 | 233(53.44%) | 166(37.73%) | 111(25.17%) | 68(15.49%) | |
| ≥ 24, < 28 | 180(41.28%) | 212(48.18%) | 258(58.50%) | 245(55.81%) | |
| ≥ 28 | 23(5.28%) | 62(14.09%) | 72(16.33%) | 126(28.70%) | |
| SBP (mmHg) | 130.49 ± 18.44 | 131.31 ± 17.12 | 129.70 ± 18.21 | 133.00 ± 18.61 | 0.046 |
| DBP (mmHg) | 77.33 ± 11.62 | 78.70 ± 10.73 | 78.71 ± 12.04 | 80.71 ± 12.25 | < 0.001 |
| TC (mmol/L) | 4.96 ± 0.94 | 4.94 ± 0.99 | 4.83 ± 0.93 | 4.79 ± 1.00 | 0.019 |
| TG (mmol/L) | 1.22(0.92–1.63) | 1.42(1.04–1.87) | 1.73(1.27–2.29) | 2.22(1.59–3.02) | < 0.001 |
| LDL-C (mmol/L) | 2.87 ± 0.81 | 3.04 ± 0.83 | 3.00 ± 0.75 | 2.99 ± 0.78 | 0.008 |
| TP (g/L) | 70.95 ± 4.00 | 71.29 ± 4.71 | 71.61 ± 3.95 | 71.73 ± 3.98 | 0.028 |
| Hb (g/L) | 150.18 ± 9.68 | 152.23 ± 10.37 | 152.70 ± 9.77 | 152.85 ± 10.59 | < 0.001 |
| TB (µmol/L) | 14.29 ± 5.57 | 13.56 ± 5.30 | 13.50 ± 5.33 | 12.68 ± 5.29 | < 0.001 |
| ALT (U/L) | 17.95(14.10–24.50) | 19.85(14.97–28.65) | 22.60(16.90–30.60) | 25.10(18.10-35.95) | < 0.001 |
| AST (U/L) | 20.00(16.80–24.70) | 20.10(16.80–24.10) | 20.20(17.00-24.10) | 20.70(17.35–25.50) | 0.292 |
| ALP (U/L) | 66.51 ± 14.78 | 67.80 ± 17.43 | 67.80 ± 16.84 | 69.24 ± 17.79 | 0.155 |
| GGT (U/L) | 22.75(17.70-35.05) | 25.90(19.50-36.95) | 30.00(21.20–43.30) | 32.10(22.90-48.45) | < 0.001 |
| FBG (mmol/L) | 5.16 ± 0.59 | 5.16 ± 0.55 | 5.24 ± 0.58 | 5.21 ± 0.59 | 0.088 |
| Serum creatinine (µmol/L) | 72.63 ± 10.00 | 74.96 ± 10.62 | 75.97 ± 12.14 | 77.77 ± 13.65 | < 0.001 |
| LFC (%) | 7.25 ± 3.51 | 8.57 ± 4.44 | 9.47 ± 4.84 | 11.43 ± 5.80 | < 0.001 |
| Female (n= 1153) | |||||
| UHR (%) | Q1(5.52–14.40) | Q2(14.41–17.96) | Q3(17.97–22.17) | Q4(22.27–43.13) | P value |
| Age (years) | 51.07 ± 9.66 | 51.00 ± 10.14 | 52.56 ± 10.72 | 53.34 ± 9.93 | 0.011 |
| Nationality (%) | 0.789 | ||||
| non-Han nationality | 5(1.74%) | 5(1.75%) | 6(2.08%) | 3(1.03%) | |
| Han nationality | 283(98.26%) | 281(98.25%) | 282(97.92%) | 288(98.97%) | |
| Marital status (%) | 0.214 | ||||
| Not married | 10(3.47%) | 13(4.55%) | 7(2.43%) | 5(1.72%) | |
| Married | 278(96.53%) | 273(95.45%) | 281(97.57%) | 286(98.28%) | |
| BMI (kg/m2), (%) | < 0.001 | ||||
| < 24 | 230(79.86%) | 200(69.93%) | 158(54.86%) | 122(41.92%) | |
| ≥ 24, < 28 | 50(17.36%) | 70(24.48%) | 102(35.42%) | 125(42.96%) | |
| ≥ 28 | 8(2.78%) | 16(5.59%) | 28(9.72%) | 44(15.12%) | |
| SBP (mmHg) | 124.64 ± 17.79 | 123.86 ± 19.67 | 126.60 ± 17.73 | 130.06 ± 21.17 | < 0.001 |
| DBP (mmHg) | 73.02 ± 10.47 | 73.71 ± 12.21 | 74.17 ± 10.45 | 76.01 ± 11.72 | 0.011 |
| TC (mmol/L) | 5.25 ± 0.89 | 5.23 ± 0.91 | 5.05 ± 0.94 | 5.02 ± 0.96 | 0.002 |
| TG (mmol/L) | 1.00(0.82–1.28) | 1.17(0.86–1.50) | 1.31(1.02–1.72) | 1.72(1.25–2.25) | < 0.001 |
| LDL-C (mmol/L) | 2.83 ± 0.72 | 3.05 ± 0.78 | 3.03 ± 0.81 | 3.05 ± 0.79 | < 0.001 |
| TP (g/L) | 71.62 ± 4.10 | 71.53 ± 3.57 | 71.73 ± 3.81 | 72.23 ± 3.94 | 0.186 |
| Hb (g/L) | 128.90 ± 11.80 | 131.33 ± 10.62 | 130.64 ± 11.31 | 132.96 ± 10.83 | < 0.001 |
| TB (µmol/L) | 11.13 ± 4.44 | 10.72 ± 4.39 | 10.27 ± 3.58 | 10.68 ± 4.26 | 0.155 |
| ALT (U/L) | 14.00(11.07–18.42) | 15.10(11.20–19.80) | 15.65(12.30-21.32) | 17.20(13.15–23.95) | < 0.001 |
| AST (U/L) | 18.70(15.60-22.42) | 18.55(15.00-22.78) | 18.50(15.90-22.92) | 18.90(16.20-22.75) | 0.408 |
| ALP (U/L) | 62.98 ± 21.51 | 64.60 ± 18.92 | 69.89 ± 20.10 | 73.23 ± 19.70 | < 0.001 |
| GGT (U/L) | 14.50(11.80–17.80) | 15.75(12.43–20.60) | 17.40(13.67–23.82) | 19.30(15.40–26.10) | < 0.001 |
| FBG (mmol/L) | 4.91 ± 0.49 | 4.93 ± 0.45 | 5.03 ± 0.52 | 5.14 ± 0.50 | < 0.001 |
| Serum creatinine (µmol/L) | 55.58 ± 7.76 | 56.86 ± 8.18 | 56.48 ± 8.24 | 59.55 ± 11.98 | < 0.001 |
| LFC (%) | 5.22 ± 2.63 | 6.02 ± 3.29 | 7.13 ± 3.34 | 9.39 ± 5.67 | < 0.001 |
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol; TP, total protein; Alb, albumin; Hb, hemoglobin; TB, total bilirubin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; GGT glutamyl transpeptidase; FBG, fasting blood glucose; LFC, Liver fat content; %, weighted percentage.