Table 3.
Protein–protein interaction enrichment analysis of total differentially expressed genes (Metascape, Access 2023.12.15).
| MCODE | GO | Description | Log10(P) |
|---|---|---|---|
| MCODE_1 | R-HSA-72766 | Translation | − 14.0 |
| MCODE_1 | R-HSA-156842 | Eukaryotic Translation Elongation | − 12.5 |
| MCODE_1 | R-HSA-975956 | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | − 12.4 |
| MCODE_2 | R-HSA-3214858 | RMTs methylate histone arginines | − 8.5 |
| MCODE_2 | R-HSA-9645723 | Diseases of programmed cell death | − 8.0 |
| MCODE_2 | GO:0070828 | Heterochromatin organization | − 7.8 |
| MCODE_3 | R-HSA-432722 | Golgi Associated Vesicle Biogenesis | − 13.7 |
| MCODE_3 | R-HSA-199992 | Trans-Golgi Network Vesicle Budding | − 13.2 |
| MCODE_3 | R-HSA-199991 | Membrane Trafficking | − 8.4 |
| MCODE_4 | R-HSA-6807878 | COPI-mediated anterograde transport | − 12.4 |
| MCODE_4 | R-HSA-199977 | ER to Golgi Anterograde Transport | − 11.5 |
| MCODE_4 | R-HSA-948021 | Transport to the Golgi and subsequent modification | − 11.1 |
| MCODE_5 | R-HSA-9033241 | Peroxisomal protein import | − 10.8 |
| MCODE_5 | R-HSA-9609507 | Protein localization | − 9.1 |
| MCODE_5 | hsa04146 | Peroxisome | − 7.1 |
| MCODE_6 | R-HSA-6807505 | RNA polymerase II transcribes snRNA genes | − 10.5 |
| MCODE_6 | CORUM:1154 | DSS1 complex | − 9.7 |
| MCODE_6 | CORUM:1153 | Integrator complex | − 9.7 |
| MCODE_9 | R-HSA-193648 | NRAGE signals death through JNK | − 8.2 |
| MCODE_9 | R-HSA-204998 | Cell death signalling via NRAGE, NRIF and NADE | − 7.8 |
| MCODE_9 | R-HSA-416482 | G alpha (12/13) signalling events | − 7.8 |