Table 6.
Protein–protein interaction enrichment analysis of up-regulated differentially expressed genes (Metascape, Access 2023.12.15).
| MCODE | GO | Description | Log10(P) |
|---|---|---|---|
| MCODE_1 | R-HSA-3214858 | RMTs methylate histone arginines | − 9.2 |
| MCODE_1 | R-HSA-9645723 | Diseases of programmed cell death | − 8.7 |
| MCODE_1 | R-HSA-5578749 | Transcriptional regulation by small RNAs | − 8.7 |
| MCODE_2 | GO:0098662 | Inorganic cation transmembrane transport | − 5.6 |
| MCODE_2 | GO:0098655 | Monoatomic cation transmembrane transport | − 5.5 |
| MCODE_2 | GO:0098660 | Inorganic ion transmembrane transport | − 5.3 |
| MCODE_3 | R-HSA-432722 | Golgi Associated Vesicle Biogenesis | − 11.0 |
| MCODE_3 | R-HSA-199992 | Trans-Golgi Network Vesicle Budding | − 10.5 |
| MCODE_3 | R-HSA-199991 | Membrane Trafficking | − 6.7 |
| MCODE_4 | R-HSA-2033519 | Activated point mutants of FGFR2 | − 9.8 |
| MCODE_4 | R-HSA-5654221 | Phospholipase C-mediated cascade FGFR2 | − 9.8 |
| MCODE_4 | R-HSA-190241 | FGFR2 ligand binding and activation | − 9.6 |