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. 2024 Dec 28;14:31290. doi: 10.1038/s41598-024-82741-9

Table 4.

Patient characteristics in relation to the FLIS.

FLIS = 6 (n = 185) FLIS < 6 (n = 50) P
Sex, male, n (%) 142 (76.8) 34 (68.0) 0.205
Median age (years) 72 74 0.332
HBV infection, yes, n (%) 43 (23.2) 7 (14.0) 0.177
HCV infection, yes, n (%) 52 (28.1) 19 (38.0) 0.224
Number of tumors, median 1 1 0.764
Solitary, n (%) 141 (76.2) 37 (74.0) 0.715
Largest tumor size (cm), median 3.4 4.1 0.032
Largest tumor size, > 3 cm, n (%) 100 (54.1) 31 (62.0) 0.340
Serum AFP level (ng/mL), median 8.3 11.7 0.507
Child–Pugh grade, A, n (%) 183 (98.9) 44 (88.0) 0.001
ALBI grade, I, n (%) 184 (99.5) 47 (94.0) 0.031
Microscopic portal vein invasion, +, n (%) 28 (15.1) 15 (30.0) 0.023
Microscopic hepatic vein invasion, +, n (%) 9 (4.9) 3 (6.0) 0.722
Microvascular invasion, +, n (%) 37 (20.0) 18 (36.0) 0.024
Surgical procedure, minor resection, n (%) 163 (88.1) 39 (78.0) 0.105
Anatomic resection, n (%) 142 (76.8) 32 (64.0) 0.072

Values represent the number of patients or mean or median values, as indicated.

FLIS Functional liver imaging score, HBV Hepatitis B virus, HCV Hepatitis C virus, AFP alpha-fetoprotein, ALBI albumin–bilirubin grade.