Table 2.
Effects of various doses of β-myrcene on the serum level of liver enzymes aspartate aminotransferase (AST), alanine transferase (ALT) and alkaline transferase (ALP), total protein (TP), bilirubin (TB), and ammonia in Thioacetamide (TAC)-induced acute hepatic encephalopathy in rats.
| Groups | AST (IU/L) | ALT (IU/L) | ALP (IU/L) | TB (mg/dL) | Ammonia (µg/dL) |
|---|---|---|---|---|---|
| Normal saline (control) | 161.6±23.3 | 74.7±8.6 | 217.3±16.4 | 0.34 ±0.16 | 107.66±13.3 |
| TAC (500 mg/kg) | 431.3±36.6* | 266.3±21.0* | 492.6±46.6* | 1.86± 0.33* | 519.6±36.6* |
| TAC + β-myrcene (10 mg/kg) | 315.3±26.6* | 177.4±19.6* | 401.3±28.6* | 0.93±0.51* | 446.6±41.3* |
| TAC + β-myrcene (25 mg/kg) | 244.3±19.6*, φ | 116.3±13.3 φ | 306.3±25.6*φ | 0.66±0.33 φ | 306.3±26.6*, φ |
| TAC + β-myrcene (50 mg/kg) | 191.3±23.6 φ | 89.6±8.3 φ | 239.6±31.3 φ | 0.56±0.16 φ | 212.3±36.6*, φ |
| β-myrcene (50 mg/kg) | 172.6±20.3 φ | 80.6±10.3 φ | 251.6±15.2 φ | 0.51±0.13 φ | 98.6±13.3 φ |
*
p<0.001 significant difference compared with control group.
φ
p<0.001 significant difference compared with TAC group.