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. 2024 Dec 16;4:1491053. doi: 10.3389/fopht.2024.1491053

Table 2.

Results of PD-1 MFI ratio and percentage of PD-1 expression on T cells in flow cytometry analysis with TED (n = 16) and control (n = 7) patients.

TED Control Remarks
MFI
CD4+ T cells 1.23 ± 0.09 1.24 ± 0.16 P = 0.97
Foxp3high CD45RA- of CD4+ T cells 2.01 ± 0.51 1.49 ± 0.24 P = 0.004
CD127- CD25+ of CD4+ T cells (Tregs) 1.65 ± 0.27 1.35 ± 0.10 P = 0.001
CD8+ T cells 1.17 ± 0.11 1.16 ± 0.17 P = 0.93
PD-1 expression (%)
CD4+ T cells 12.89 ± 4.49 6.02 ± 2.17 P < 0.001
Foxp3high CD45- T cells 28.03 ± 13.95 12.47 ± 4.99 P = 0.001
CD8+ T cells 17.89 ± 10.68 11.07 ± 5.82 P = 0.09

TED, thyroid eye disease.

MFI, mean fluorescence intensity.

Italics indicate items for which significant differences were found.