Table 2.
Results of PD-1 MFI ratio and percentage of PD-1 expression on T cells in flow cytometry analysis with TED (n = 16) and control (n = 7) patients.
TED | Control | Remarks | |
---|---|---|---|
MFI | |||
CD4+ T cells | 1.23 ± 0.09 | 1.24 ± 0.16 | P = 0.97 |
Foxp3high CD45RA- of CD4+ T cells | 2.01 ± 0.51 | 1.49 ± 0.24 | P = 0.004 |
CD127- CD25+ of CD4+ T cells (Tregs) | 1.65 ± 0.27 | 1.35 ± 0.10 | P = 0.001 |
CD8+ T cells | 1.17 ± 0.11 | 1.16 ± 0.17 | P = 0.93 |
PD-1 expression (%) | |||
CD4+ T cells | 12.89 ± 4.49 | 6.02 ± 2.17 | P < 0.001 |
Foxp3high CD45- T cells | 28.03 ± 13.95 | 12.47 ± 4.99 | P = 0.001 |
CD8+ T cells | 17.89 ± 10.68 | 11.07 ± 5.82 | P = 0.09 |
TED, thyroid eye disease.
MFI, mean fluorescence intensity.
Italics indicate items for which significant differences were found.