Table 3.

Results of multivariate regression analysis: correlation with clinical factors between age, gender, and patient type (TED or control patient).

Variable	Regression coefficient	95%CI	P-value
A. MFI for the CD4+ T cells.
Age	0.006	0.003 0.009	<0.001
Gender	-0.138	-0.214 -0.062	0.001
TED/Control	0.049	-0.047 0.145	0.30
B. MFI for the Foxp3high CD45RA- of the CD4+ T cells.
Age	-0.008	-0.026 0.009	0.32
Gender	-0.166	-0.615 -0.283	0.45
TED/Control	-0.747	-1.314 - -0.180	0.01
C. MFI for the CD127-CD25+ of the CD4+ T cells (Tregs).
Age	0.003	-0.006 - 0.011	0.49
Gender	-0.170	-0.394 - 0.055	0.13
TED/Control	-0.316	-0.599 - -0.033	0.03
D. MFI for the CD8+ T cells.
Age	0.002	-0.003 - 0.007	0.36
Gender	-0.045	-0.178 - 0.087	0.48
TED/Control	0.014	-0.053 - 0.182	0.86
E. PD-1 expression on the CD4 T cells.
Age	0.068	-0.062 - 0.197	0.29
Gender	-4.769	-8.144 - -1.394	0.008
TED/Control	-7.664	-11.922 - -3.406	0.001
F. PD-1 expression on the FOXP3 high CD45- T cells.
Age	-0.074	-0.398 - 0.546	0.75
Gender	-5.261	-17.575 - 7.053	0.38
TED/Control	-16.458	-31.994 - -0.921	0.04
G. PD-1 expression on the CD8 T cells.
Age	0.137	-0.225 - 0.498	0.44
Gender	-5.948	-15.374 - 3.478	0.20
TED/Control	-6.891	-18.784 - 5.002	0.24

Italics indicate items for which significant differences were found.