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. 2024 Nov 28;104(1):151–163. doi: 10.1111/aogs.15020

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© 2024 The Author(s). Acta Obstetricia et Gynecologica Scandinavica published by John Wiley & Sons Ltd on behalf of Nordic Federation of Societies of Obstetrics and Gynecology (NFOG).

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Combined marker analysis of prediction pregnancy complications. Top: Receiver Operating Characteristic (ROC) curve made of the sensitivity and the specificities of univariate and multiple pairs of total and placental surface markers. Bottom: The calculated area under ROC curve (AUROC), and its respective sensitivities at 90% and 80% specificities shows the added value of adding each pair. Left: PE vs TD control, Middle: PTD vs TD control, and Right: PE vs PTD. Marker nature is provided in Table 1.