TABLE 2.
Characterization of the study population—pregnancy and delivery features.
| Parameter | Term control delivery at GA > 37 weeks (n = 15) | PE (n = 19) | PTD delivery < 37 weeks (n = 16) | p |
|---|---|---|---|---|
| Maternal age (years) | 30.0 [27.0–33.0] | 32.0 [30.0–36.0] | 30.5 [28.0–35.0] | 0.324 |
| BMI (kg/h2) | 25.0 [22.2–32.3] | 32.0 [26.0–36.0] | 27.0 [26.0–29.0] | 0.239 |
| BMI >30, n (%) | 4 (33.3) | 11 (57.9) | 2 (13.3) | 0.132 |
| Smoker, n (%) | 4 (26.7) | 10 (52.6) | 9 (56.3) | 0.573 |
| Previous PE, n (%) | 0 (0) | 5 (26.3) | 5 (31.3) | 0.125 |
| Nulliparity, n (%) | 2 (13.3) | 0 (0) | 0 (0) | 0.247 |
| Conception by IVF, n (%) | 0 (0) | 1 (5.3) | 0 (0) | 0.879 |
| Previous GDM, n (%) | 2 (13.3) | 2 (10.5) | 2 (12.5) | 0.765 |
| Chronic hypertension n, (%) | 0 (0) | 3 (15.8) | 0 (0) | 0.201 |
| Diabetes mellitus 0 (%) | 2 (13.3) | 1 (5.3) | 0 (0) | 0.614 |
| Systolic BP (mm Hg) | 109b [105–119] | 162a [150–180] | 123b [115–128] | <0.001 |
| Diastolic BP (mm Hg) | 71b [69–75] | 100a [90–107] | 77b [73–80] | <0.001 |
| MAP (mm Hg) | 84b [81–90] | 118a [108–133] | 91b [88–96] | <0.001 |
| Creatinine (mg/dL) | 0.50b [0.4–0.6] | 0.70a [0.6–0.8] | 0.5b [0.5–0.6] | 0.004 |
| Aspirin, n (%) | 0 (0) | 3 (17.6) | 1 (6.3) | 0.020 |
| GA at delivery (wks) | 39.1a [38.7–39.9] | 37.1b [35.0–37.4] | 36.2b [34.7–36.6] | <0.001 |
| Infant's birthweight (gr) | 3290a [2840–3620] | 2730b [2180–3125] | 2498b [2235–3068] | <0.001 |
| Infant gender (male) n (%) | 10 (66.7) | 10 (55.6) | 16 (100) | 0.036 |
| NICU days | 39.1a [38.7–39.9] | 37.1b [35.0–37.4] | 36.2b [34.7–36.6] | <0.001 |
Note: Continuous variables are shown as medians and the interquartile range [IQR], and categorical variables are shown as frequencies—n, and percentages (%). The letters “a” “b” represent significant differences between the groups' medians using the Kruskal–Wallis non‐parametric test. The letter “a” is significantly higher, “b” is significantly lower than “a”.
Abbreviations: BMI, body mass index; BP, blood pressure; GA, gestational week; GDM, gestational diabetes melilotus; IVF, in vitro fertilization; MAP, mean arterial blood pressure; NICU, newborn intensive care unit; NICU, newborn intensive care unit; PE, preeclampsia; PTD, preterm delivery.
Bold indicate a P‐value below 0.05.