FIGURE 2:
Comparison analysis of enriched canonical pathways. Enrichment analysis was conducted using Ingenuity Pathway Analysis for each treatment group. Clustering was done using all significantly enriched pathways. For graphing purposes, nonsignificant pathways for a given treatment group were assigned a value of 0.5; only the top 25 pathways are displayed. CLEAR = coordinated lysosomal expression and regulation; TR/RXR = thyroid hormone receptor/retinoid X receptor; NRF1 = nuclear respiratory factor 1; MAPK = mitogen-activated protein kinase; LPS/IL-1 = lipopolysaccharide/interleukin 1; LXR = liver X receptor; PXR = pregnane X receptor; FXR = farnesoid X receptor; dpf = days postfertilization.