Table 3.

Changes of myofilaments and supporting structures in cirrhotic cardiomyocytes.

Myofilaments	Structural or functional change	Impact on cardiac function
MHC [31]	Switch from $\alpha$-MHC to $\beta$-MHC	Reduces contractile force and velocity
Collagen [64]	Switch from type III to type I	Increases diastolic stiffness

MHC, myosin heavy chain.