. 2024 Dec 25;25(12):461. doi: 10.31083/j.rcm2512461

Table 2A.

Univariable and multivariable cox proportional hazard models for serum CAR in all heart failure.

	Univariable		Multivariable
	HR (95% CI)	p	HR (95% CI)	p
Age	1.030 (1.023, 1.038)	$<$ 0.001	1.024 (1.016, 1.033)	$<$ 0.001
Sex (reference: male)	1.037 (0.874, 1.230)	0.680	0.991 (0.823, 1.193)
NYHA class (reference: class IV)	0.412 (0.349, 0.486)	$<$ 0.001	0.491 (0.412, 0.586)	$<$ 0.001
LVEF	0.994 (0.989, 1.000)	0.033	1.000 (0.993, 1.006)
Heart rate	1.007 (1.003, 1.010)	$<$ 0.001	1.005 (1.001, 1.009)	0.020
SBP	0.994 (0.990, 0.998)	0.001	0.999 (0.993, 1.004)
DBP	0.985 (0.980, 0.991)	$<$ 0.001	0.992 (0.984, 1.000)
CRP	1.011 (1.009, 1.012)	$<$ 0.001	1.013 (1.010, 1.018)	$<$ 0.001
Albumin	0.931 (0.913, 0.949)	$<$ 0.001	0.956 (0.934, 0.980)	$<$ 0.001
ALT	1.003 (1.002, 1.004)	$<$ 0.001	1.000 (0.998, 1.001)
AST	1.004 (1.003, 1.005)	$<$ 0.001	1.003 (1.001, 1.005)	0.004
TC	0.818 (0.749, 0.893)	$<$ 0.001	1.012 (0.927, 1.105)
Creatinine	1.003 (1.002, 1.003)	$<$ 0.001	1.000 (0.984, 1.001)
Uric acid	1.001 (1.000, 1.002)	$<$ 0.001	1.002 (1.001, 1.003)	$<$ 0.001
Chlorine	0.930 (0.914, 0.947)	$<$ 0.001	0.956 (0.939, 0.974)	$<$ 0.001
WBC	1.051 (1.030, 1.071)	$<$ 0.001	1.057 (1.035, 1.061)
Hemoglobin	0.990 (0.987, 0.994)	$<$ 0.001	0.994 (0.990, 0.998)	0.002
LgBNP	5.291 (3.888, 7.200)	$<$ 0.001	2.815 (1.949, 4.066)	$<$ 0.001
CAR	1.004 (1.003, 1.005)	$<$ 0.001	1.006 (1.002, 1.009)	0.019

Corrected for age, NYHA class, heart rate, SBP, DBP, CRP, albumin, ALT, AST, TC, creatinine, uric acid, chlorine, WBC, hemoglobin, lgBNP.

HR, hazard ratio; CI, confidence interval; CAR, c-reactive protein-to-albumin ratio; NYHA, New York Heart Association; LVEF, left ventricular ejection fraction; SBP, systolic blood pressure; DBP, diastolic blood pressure; CRP, c-reactive protein; ALT, alanine transaminase; AST, aspartate transaminsae; TC, total cholesterol; WBC, white blood cells; BNP, brain natriuretic peptide.