Table 2.
Effect of L-carnitine (LCAR, 300 and 500 mg/kg/day, IP) on serum lipid profile in dexamethasone (DEXA)-toxified rats
| Control | DEXA | DEXA-MET | LCAR500 | DEXA-LCAR300 | DEXA-LCAR500 | |
|---|---|---|---|---|---|---|
| Total cholesterol (mg/dL) | 101.60 ± 7.55 | 195.00 ± 31.70* | 184.40 ± 41.20* | 112.00 ± 19.28 | 151.20 ± 17.33* | 154.00 ± 27.03* |
| HDL-C (mg/dL) | 65.17 ± 5.38 | 41.71 ± 5.02* | 69.50 ± 15.77# | 64.00 ± 16.97 | 65.00 ± 9.21# | 68.00 ± 6.93# |
| Non-HDL-C (mg/dL) | 36.33 ± 6.77 | 152.70 ± 32.71* | 115.00 ± 27.60*# | 47.50 ± 2.88 | 86.17 ± 12.53*# | 86.00 ± 20.34*# |
|
TGs (mg/dL) |
98.33 ± 19.16 | 396.50 ± 212.8* | 211.00 ± 63.78# | 113.80 ± 57.27 | 200.80 ± 80.24# | 161.00 ± 40.58# |
Data are shown as means ± SD, n = 6 per group
HDL-C, high-density lipoprotein cholesterol; TGs, triglycerides
*, #P < 0.05 versus control and DEXA groups, respectively