Table 2.
Multivariable Survival Analysis in the Confirmation Cohort (n = 156) Using Parameters Available at the Time of Diagnosis
| PFS | OS | |||
|---|---|---|---|---|
| Variable [Ref] | HR (95% CI) | p value | HR (95% CI) | p value |
| Age | 1.036(1.009–1.064) | 0.010 | ||
| Stage [III] | 0.009 | |||
| IV | 2.137(1.098–4.160) | |||
| Recur | 2.335(1.240–4.398) | |||
| CA-125 | 1.001(1.000–1.002) | 0.061 | ||
| BMI | 0.866(0.768–0.976) | 0.018 | ||
| Radiotherapy[No] | 0.074 | |||
| Yes | 0.367(0.122–1.101) | |||
| Molecular classification [p53wt/pMMR] | 0.039 | 0.172 | ||
| dMMR | 0.579(0.258–1.300) | 0.000(0.000–5.407E173) | ||
| p53abn | 1.599(0.911–2.806) | 2.430(0.960–6.151) | ||
HR Hazard ratio, Recur recurrent endometrial cancer, dMMR mismatch repair protein deficiency, p53wt/pMMR p53-wild with proficient mismatch repair, p53abn abnormal p53, BMI body mass index