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. 2024 Dec 30;24:1586. doi: 10.1186/s12885-024-13294-3

Table 2.

Multivariable Survival Analysis in the Confirmation Cohort (n = 156) Using Parameters Available at the Time of Diagnosis

PFS OS
Variable [Ref] HR (95% CI) p value HR (95% CI) p value
Age 1.036(1.009–1.064) 0.010
Stage [III] 0.009
IV 2.137(1.098–4.160)
Recur 2.335(1.240–4.398)
CA-125 1.001(1.000–1.002) 0.061
BMI 0.866(0.768–0.976) 0.018
Radiotherapy[No] 0.074
Yes 0.367(0.122–1.101)
Molecular classification [p53wt/pMMR] 0.039 0.172
dMMR 0.579(0.258–1.300) 0.000(0.000–5.407E173)
p53abn 1.599(0.911–2.806) 2.430(0.960–6.151)

HR Hazard ratio, Recur recurrent endometrial cancer, dMMR mismatch repair protein deficiency, p53wt/pMMR p53-wild with proficient mismatch repair, p53abn abnormal p53, BMI body mass index