Table 4.

Threshold effect analysis of the hs-CRP/HDL-C ratio on long-term all-cause and cardiovascular mortality by using two-piecewise linear regression

	All-cause mortality		Cardiovascular mortality
	HR (95% CI)	P value	HR (95% CI)	P value
Fitting by standard linear model	1.09 (1.05, 1.13)	< 0.001	1.11 (1.05, 1.19)	0.001
Fitting by two-piecewise linear model
Inflection point	1.21		1.53
< Inflection point	1.92 (1.39, 2.65)	< 0.001	2.09 (1.25, 3.49)	0.005
≥ Inflection point	1.09 (1.05, 1.13)	< 0.001	1.11 (1.04, 1.19)	0.003
Log likelihood ratio	0.008		0.078

HR, hazard ratio; CI, confidence interval. Adjusted for age, sex, race, drinking, smoking, BMI, hypertension, diabetes, heart failure, coronary artery disease, stroke and lipid-lowering drugs