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. 2025 Jan 21;31(3):102283. doi: 10.3748/wjg.v31.i3.102283

Table 1.

Patient characteristics in the training and test cohorts

Clinical characteristics Training cohort (n = 55)
Test cohort (n = 18)
MH
Non-MH
P value
MH
Non-MH
P value
Age (year) 27.32 ± 11.73 34.81 ± 10.93 0.007 31.67 ± 8.50 40.92 ± 13.91 0.158
Gender, n (%) 0.384 0.316
Male 16 (84.21) 25 (69.44) 6 (100.00) 8 (66.67)
Female 3 (15.79) 11 (30.56) 0 (0.00) 4 (33.33)
Disease duration, months 27.11 (23.50) 48.58 (43.50) 0.021 25.67 (3.00) 49.83 (37.00) 0.11
Montreal location, n (%) 0.715 0.761
L1 13 (68.42) 20 (55.56) 4 (66.67) 7 (58.33)
L3 4 (21.05) 12 (33.33) 2 (33.33) 4 (33.33)
L1 + L4 1 (5.26) 3 (8.33) 0 (0.00) 1 (8.33)
L3 + L4 1 (5.26) 1 (2.78) 0 (0.00) 0 (0.00)
Montreal behavior, n (%) 0.219 0.187
B1 15 (78.95) 21 (58.33) 4 (66.67) 3 (25.00)
B2 4 (21.05) 12 (33.33) 1 (16.67) 7 (58.33)
B3 0 (0.00) 3 (8.33) 1 (16.67) 2 (16.67)
Perianal involvement, n (%) 13 (68.42) 10 (27.78) 0.009 1 (16.67) 3 (25.00) 1.000
Treatment history, n (%)
5-aminosalicylic acid 2 (10.53) 5 (13.89) 1.00 0 (0.00) 0 (0.00) 1.000
Steroids 4 (21.05) 15 (41.67) 0.218 2 (33.33) 5 (41.67) 1.000
Immunomodulator 4 (21.05) 19 (52.78) 0.048 2(33.33) 5 (41.67) 1.000
Anti-TNF agent 17 (89.47) 27 (75.00) 0.357 4 (66.67) 9 (75.00) 1.000
Smoking history, n (%) 3 (15.79) 6 (16.67) 1.000 3 (50.00) 3 (25.00) 0.596
CDAI, mean (IQR) 63.51 (31.09) 92.84 (89.14) 0.589 51.72 (35.21) 82.96 (62.13) 0.200
BMI (mean ± SD) 20.98 ± 3.28 21.15 ± 3.73 0.937 23.75 ± 5.06 20.60 ± 1.99 0.250
WBC (× 109/L) 5.69 ± 1.56 5.97 ± 1.92 0.586 5.50 ± 2.40 5.08 ± 1.64 0.779
NLR 1.67 ± 0.70 2.47 ± 1.11 0.006 1.93 ± 1.17 3.80 ± 5.71 0.335
HB (g/L) 139.58 ± 11.79 120.19 ± 27.90 0.004 136.83 ± 15.94 132.08 ± 23.51 0.664
HCT (%) 42.07 ± 3.50 37.12 ± 7.34 0.004 41.05 ± 4.81 39.61 ± 6.49 0.638
ALB (g/L) 42.55 ± 2.85 39.07 ± 4.75 0.006 42.60 ± 1.41 38.87 ± 5.24 0.068
CRP (mg/dL) 2.56 (1.44) 9.86 (8.38) 0.000 1.51 (0.24) 9.00 (10.64) 0.067
CPT (μg/g) 348.02 (455.37) 513.29 (410.31) 0.012 349.45 (374.54) 677.13 (258.78) 0.111

ALB: Albumin; BMI: Body mass index; CDAI: Clinical disease activity index; CPT: Calprotectin; CRP: C-reactive protein; HB: Haemoglobin; HCT: Haematocrit; NLR: Neutrophil-to-lymphocyte ratio; TNF: Tumor necrosis factor; WBC: White blood cell.