Table 1.
Compared different baseline information between non-surgical adverse events and surgical adverse events patients, n (%)
|
Train set (n = 549)
|
Validation set (n = 198)
|
|||||
|
Non-SAE (n = 493)
|
SAE (n = 56)
|
P value
|
Non-SAE (n = 171)
|
SAE (n = 27)
|
P value
|
|
| Age, mean ± SD | 61.11 ± 7.32 | 65.77 ± 5.43 | < 0.001a | 61.87 ± 7.28 | 64.15 ± 7.17 | 0.131 |
| Gender (male) | 397 (80.5) | 40 (71.4) | 0.109 | 130 (76.0) | 19 (70.4) | 0.527 |
| BMI, mean ± SD | 22.10 ± 2.76 | 21.65 ± 3.09 | 0.252 | 21.81 ± 2.76 | 22.11 ± 2.92 | 0.604 |
| Smoke (+) | 76 (53.5) | 115 (59.9) | 0.224 | 102 (59.6) | 16 (59.3) | 0.969 |
| History of alcohol consumption (+) | 43 (30.3) | 61 (31.8) | 0.771 | 42 (24.6) | 8 (29.6) | 0.573 |
| Diabetes (+) | 35 (7.1) | 4 (7.1) | 0.990 | 10 (5.8) | 2 (7.4) | 0.752 |
| HBP (+) | 99 (20.1) | 15 (26.8) | 0.241 | 32 (18.7) | 3 (11.1) | 0.336 |
| CHD (+) | 35 (7.1) | 6 (10.7) | 0.329 | 10 (5.8) | 2 (7.4) | 0.752 |
| COPD (+) | 11 (2.2) | 7 (12.5) | < 0.001a | 3 (1.8) | 4 (14.8) | 0.007a |
| Tumor location | 0.057 | 0.856 | ||||
| Upper thoracic | 39 (7.9) | 1 (1.8) | 11 (6.4) | 1 (3.7) | ||
| Middle thoracic | 194 (39.4) | 30 (53.6) | 69 (40.4) | 11 (40.7) | ||
| Lower thoracic | 260 (52.7) | 25 (44.6) | 91 (53.2) | 15 (55.6) | ||
| Neoadjuvant therapy (+) | 277 (56.2) | 25 (44.6) | 0.100 | 83 (48.5) | 14 (51.9) | 0.749 |
| pT | 0.857 | 0.117 | ||||
| 0 | 55 (11.2) | 8 (14.3) | 17 (9.9) | 4 (14.8) | ||
| 1 | 154 (31.2) | 17 (30.4) | 55 (32.2) | 4 (14.8) | ||
| 2 | 77 (15.6) | 7 (12.5) | 30 (17.5) | 9 (33.3) | ||
| 3 | 207 (42.0) | 24 (42.9) | 69 (40.4) | 10 (37.0) | ||
| 4 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | ||
| pN | 0.746 | 0.509 | ||||
| 0 | 285 (57.8) | 36 (64.3) | 99 (57.9) | 18 (66.7) | ||
| 1 | 122 (24.7) | 13 (23.2) | 41 (24.0) | 3 (11.1) | ||
| 2 | 69 (14.0) | 6 (10.7) | 27 (15.8) | 5 (18.5) | ||
| 3 | 17 (3.4) | 1 (1.8) | 4 (2.3) | 1 (3.7) | ||
P < 0.05.
SAE: Surgical adverse events; BMI: Body mass index; HBP: High blood pressure; CHD: Coronary heart disease; COPD: Chronic obstructive pulmonary disease.