Table 3.

Univariate and multivariate analysis of influencing factors

Variable	Univariate			Multivariate
	OR	95%CI	P value	OR	95%CI	P value
Age	1.10	1.05-1.14	< 0.001a	1.03	0.97-1.08	0.339
History of alcohol consumption			0.006a			< 0.001a
None	Reference			Reference
Yes	2.21	1.26-3.87		4.69	2.32-9.51
COPD			< 0.001a			0.020a
None	Reference			Reference
Yes	6.26	2.32-16.88		4.82	1.28-18.18
Neoadjuvant chemotherapy
None	Reference
Chemotherapy	0.73	0.33-1.59	0.426
Immunochemotherapy	0.60	0.32-1.13	0.113
Neoadjuvant radiotherapy			0.057			0.051
None	Reference			Reference
Yes	2.75	0.97-7.75		3.69	1.00-13.71
Tumor size	0.94	0.83-1.07	0.352
FEV1	0.13	0.07-0.23	< 0.001a	0.13	0.06-0.27	< 0.001a
Ca	0.04	0.00-0.77	0.033a	0.06	0.00-2.39	0.134
Hemoglobin	0.98	0.96-0.99	0.002a	0.99	0.97-1.00	0.119
Albumin	0.82	0.76-0.88	< 0.001a	0.83	0.76-0.90	< 0.001a

^a P < 0.05.

COPD: Chronic obstructive pulmonary disease; FEV1: Forced expiratory volume in the first second; Ca: Calcium; OR: Odds ratio; CI: Confidence interval.