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. 2025 Jan 21;31(3):99833. doi: 10.3748/wjg.v31.i3.99833

Table 2.

Logistic regression analyses for sustained Hepatitis Be antigen seroconversion at week 12

Characteristics Univariate analysis
Multivariate analysis
OR
95%CI
P value
OR
95%CI
P value
ALT 1.002 0.998-1.002 0.383 1.008 0.999-1.014 0.063
IL-21 0.999 0.994-1.004 0.645          
PDL1 0.957 0.891-1.029 0.236          
CXCR5 1.038 0.953-1.131 0.395 0.652 0.387-1.098 0.107
PDL1+CD8+ 1.070 0.959-1.193 0.225          
PDL1+CD4+ (%) 0.85 0.733-0.984 0.018a          
CXCR5+CD8+ 1.459 1.125-1.892 0.004b 4.820 1.081-21.487 0.039a
CXCR5+CD4+ 0.952 0.853-1.062 0.375               
log10 HBV DNA 0.412 0.241-0.705 0.001b               
log10 HBsAg 0.126 0.032-0.507 0.004b               
log10 HBeAg 0.300 0.144-0.626 0.001b 0.009 0.001-0.490 0.021a
a

P < 0.05.

b

P < 0.01.

ALT: Alanine aminotransferase; HBV: Hepatitis B virus; HBeAg: Hepatitis Be antigen; IL-21: Interleukin-21; CXCR5: C-X-C chemokine receptor type 5; PD-L1: Programmed death-ligand 1.