Table 2.
Differences in primary effectiveness indicators between each visit time point and baseline
| Baseline (n = 134) |
1 week (n = 133) |
2 weeks (n = 125) |
4 weeks (n = 113) |
8 weeks (n = 86) |
12 weeks (n = 61) |
Baseline VS 1 week | Baseline VS 2 weeks | Baseline VS 4 weeks | Baseline VS 8 weeks | Baseline VS 12 weeks | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| All participants | T | P | T | P | T | P | T | P | T | P | ||||||
| PANSS total score | 96.16 (20.44) | 83.69 (20.67) | 70.56 (20.48) | 61.61 (21.05) | 55.78 (21.37) | 53.77 (22.25) | –12.70 | < 0.001 | –17.35 | < 0.001 | –18.49 | < 0.001 | –18.36 | < 0.001 | –17.22 | < 0.001 |
| CGI-S score | 5.24 (0.72) | 4.64 (0.88) | 4.08 (1.13) | 3.65 (1.21) | 3.28 (1.36) | 3.16 (1.42) | –9.03 | < 0.001 | –12.30 | < 0.001 | –15.32 | < 0.001 | –16.50 | < 0.001 | –16.22 | < 0.001 |
Data are reported as mean (SD). SD standard deviation, PANSS Positive and Negative Syndrome Scale, CGI-S Clinical Global Impression-Severity. Data were analyzed with the last observation carried forward (LOCF) method