Table 1.
Characteristics of patients
| Characteristic | UC (n = 5,872) | CD (n = 1,427) | IBD-undefined (n = 434) |
|---|---|---|---|
| Sex | |||
| Male | 3,023 (51.5%) | 691 (48.0%) | 229 (53.0%) |
| Female | 2,849 (48.5%) | 736 (52.0%) | 205 (47.0%) |
| Age (years) | |||
| 18‒59 years | 3,613 (62%) | 1,117 (78.28%) | 352 (81.11%) |
| ≥ 60 years | 2,259 (39%) | 310 (21.72%) | 82 (18.89%) |
| Mean (SD) | 52.83 (19.5) | 44.03 (18.4) | 42.99 (17.6) |
| Median (range) | 55 (18‒103) | 39 (18‒100) | 39 (18‒88) |
| BMI (kg/m 2 )* | |||
| Mean (SD) | 26.5 (5.8) | 25.4 (5.4) | 26.0 (5.7) |
| Median (range) | 25.6 (9.2–58.0) | 24.8 (10.1–52.5) | 25.3 (12.4–45.6) |
| Ethnicity (%) | |||
| Asian | 1,524 (26%) | 299 (21%) | 100 (23%) |
| Black | 344 (6%) | 63 (4%) | 16 (4%) |
| Mixed race | 131 (2%) | 42 (3%) | 10 (2%) |
| White | 523 (9%) | 144 (10%) | 53 (12%) |
| Other | 411 (7%) | 105 (7%) | 36 (8%) |
| Not recorded | 2,939 (50%) | 774 (54%) | 219 (50%) |
| Smoking status | |||
| Smoker | 1,054 (18%) | 314 (22%) | 92 (21%) |
| Ex-smoker | 1,015 (17%) | 173 (12%) | 65 (15%) |
| Non-smoker | 123 (2%) | 29 (2%) | 8 (2%) |
| Not recorded | 3,680 (63%) | 911 (64%) | 269 (62%) |
| Time from diagnosis to study end (months) | |||
| < 24 | 3,000 (51%) | 681 (48%) | 209 (48%) |
| ≥ 24 | 2,872 (49%) | 746 (52%) | 225 (52%) |
| Electronic Frailty Index score | |||
| Mild | 808 (14%) | 137 (10%) | 47 (11%) |
| Moderate | 547 (9%) | 70 (5%) | 29 (7%) |
| Severe | 405 (7%) | 55 (4%) | 7 (2%) |
| Well | 3,306 (56%) | 911 (64%) | 290 (67%) |
| Not recorded | 806 (14%) | 254 (18%) | 61 (14%) |
| At least one comorbidity | |||
| Number | 2,960 (50%) | 586 (41%) | 177 (40%) |
| Mean (SD) | 2.0 (1.2) | 1.8 (1.0) | 1.8 (1.2) |
| Median (range) | 2 (1‒7) | 1 (1‒8) | 1 (1‒7) |
| Disease activity status at baseline | |||
| Active disease | 2,040 (35%) | 483 (34%) | 263 (60%) |
| 18‒59 years | 1,409 (69%) | 393 (81%) | 210 (80%) |
| ≥ 60 years | 631 (31%) | 90 (19%) | 53 (20%) |
| Remission | 3,832 (65%) | 944 (66%) | 171 (40%) |
| 18‒59 years | 2,204 (58%) | 724 (77%) | 91 (83%) |
| ≥ 60 years | 1,628 (42%) | 220 (23%) | 29 (17%) |
| Biologic treatment | |||
| Yes | 177 (3%) | 122 (9%) | 93 (21%) |
| Early | 70 | 37 | 37 |
| Late | 107 | 85 | 56 |
| No | 5,725 (97%) | 1,350 (91%) | 341 (79%) |
| Remission achieved | |||
| Total number of observations | 23,488 | 5,708 | 1,736 |
| Observations classified as remission | 19,218 (82%) | 4,686 (82%) | 1,122 (65%) |
*Denominators 4,171, 903, and 316 for UC, CD, and IBD-undefined, respectively. Abbreviations: CD, Crohn’s disease; IBD, inflammatory bowel disease; UC, ulcerative colitis