Table 2.
Multivariable Cox Proportional Hazards Model for Overall Survival
| Variable | HR (95% CI) | P value |
|---|---|---|
| PCS (reference: PCS ≥ 50) | ||
| PCS < 50 | 1.91 (1.69–2.17) | <0.001 |
| MCS (reference: MCS ≥ 50) | ||
| MCS < 50 | 1.18 (1.06–1.32) | 0.002 |
| Gender (reference: Female) | ||
| Male | 1.17 (1.04–1.32) | 0.01 |
| Age at Diagnosis (reference: Adolescent) | ||
| Emerging Adult | 1.48 (1.11–1.97) | 0.007 |
| Young Adult | 1.48 (1.13–1.93) | 0.005 |
| Race/Ethnicity (reference: White) | ||
| Black | 1.33 (1.13–1.57) | 0.001 |
| Hispanic | 1.09 (0.94–1.25) | 0.24 |
| Other race/ethnicity | 1.01 (0.81–1.26) | 0.94 |
| Tumor Type (reference: Breast) | ||
| Cervical | 1.08 (0.77–1.51) | 0.66 |
| CNS | 1.96 (1.47–2.61) | <0.001 |
| CRC | 1.91 (1.51–2.43) | <0.001 |
| GCT | 0.26 (0.16–0.42) | <0.001 |
| HL | 0.31 (0.21–0.45) | <0.001 |
| Leukemia | 1.44 (1.15–1.81) | 0.001 |
| NHL | 0.52 (0.38–0.71) | <0.001 |
| Sarcoma | 1.77 (1.43–2.20) | <0.001 |
| Other tumor types | 2.85 (2.37–3.42) | <0.001 |
| Diagnosis Year (continuous) | 0.99 (0.97–1.00) | 0.079 |