Table 3.

Significantly different SGBs identified between PD and PD-CI groups

SGBs	Taxonomy	Mean_PD-CI	Mean_PD	SD_PD-CI	SD_PD	P-value, Wilcoxon test
Sample_LPA21.bin_22	Clostridiales bacterium	0.18	0.52	0.30	0.79	0.01
Sample_LPA09.bin_1	Lactobacillus salivarius	4.75	0.22	15.15	0.79	0.01
Sample_LPA10.bin_4	Lactobacillus mucosae	0.66	1.02	1.66	6.27	0.01
Sample_SPA32.bin_3	Azospirillum sp.	0.01	0.63	0.05	2.21	0.01
Sample_LPA13.bin_3	uncultured Ruminococcus sp.	0.56	4.05	1.52	15.72	0.01
Sample_SPA06.bin_8	Ruminococcaceae bacterium	0.36	3.69	2.35	16.51	0.02
Sample_SPA41.bin_3	Streptococcus anginosus	1.64	0.02	9.21	0.09	0.02
Sample_SPA08.bin_5	Alistipes indistinctus	0.22	0.07	0.64	0.38	0.04
Sample_SPA32.bin_7	Eubacterium sp. CAG:274	0.07	0.46	0.40	1.37	0.05

PD: Patients with Parkinson’s disease but without cognitive impairment; PD-CI: patients with Parkinson’s disease and cognitive impairment; SGBs: species-level genomic bins.