Table 2.
Absolute counts and proportions of peripheral blood lymphocytes in the RA-Obstructive CAD, RA-Non-Obstructive CAD, and HC Groups.
| (A) | RA-Obstructive CAD (n=60) | RA-Non-Obstructive CAD (n=60) | HC (n=53) | p |
|---|---|---|---|---|
| totalT (cells/μL) | 1225.71 (970.23-1538.75) | 939.48 (730.65-1216.34) | 778.66 (548.75-1018.14) | <0.001*** |
| totalB (cells/μL) | 169.29 (96.90-304.63) | 122.35 (85.17-216.37) | 86.36 (58.00-121.82) | <0.001*** |
| CD4+ T (cells/μL) | 694.29 (595.83-962.43) | 555.07 (362.68-771.16) | 349.27 (180.89-530.56) | <0.001*** |
| CD8+ T (cells/μL) | 473.67 (368.32-568.12) | 348.34 (238.52-467.11) | 244.50 (145.35-349.55) | <0.001*** |
| NK (cells/μL) | 191.68 (142.79-275.42) | 175.55 (90.61-284.70) | 194.49 (138.39-295.09) | 0.37 |
| Th1 (cells/μL) | 103.05 (65.18-154.31) | 86.09 (50.35-135.44) | 49.24 (21.37-92.39) | <0.001*** |
| Th2 (cells/μL) | 7.08 (5.00-12.02) | 8.33 (5.70-13.17) | 5.19 (3.35-8.79) | 0.003** |
| Th17 (cells/μL) | 11.53 (6.08-18.38) | 7.33 (4.51-9.99) | 4.43 (2.72-6.47) | <0.001*** |
| Treg (cells/μL) | 23.15 (11.85-32.90) | 31.61 (17.15-42.36) | 34.93 (25.53-48.16) | <0.001*** |
| (B) | RA-Obstructive CAD (n=60) | RA-Non-Obstructive CAD (n=60) | HC (n=53) | p |
| T% | 73.90 (65.68-80.55) | 73.87 (65.81-78.14) | 66.75 (61.62-73.59) | <0.001*** |
| B% | 10.69 (6.49-14.69) | 10.78 (6.23-15.34) | 7.78 (5.11-10.00) | <0.001*** |
| CD4+ T% | 42.93 (37.19-49.27) | 41.78 (32.64-48.73) | 33.23 (25.56-40.68) | <0.001*** |
| CD8+ T% | 26.97 (20.21-36.54) | 25.15 (19.68-32.89) | 22.56 (18.55-29.83) | 0.032* |
| CD4+ T/CD8+ T | 1.67 (1.11-2.25) | 1.61 (1.11-2.18) | 1.37 (1.09-1.90) | 0.338 |
| NK% | 11.28 (8.52-17.39) | 13.38 (7.75-20.49) | 18.88 (14.60-26.01) | <0.001*** |
| Th1% | 15.95 (10.85-24.82) | 15.31 (10.55-22.54) | 14.21 (8.40-17.87) | 0.081 |
| Th2% | 1.30 (0.86-1.67) | 1.41 (1.12-1.75) | 1.25 (0.81-1.64) | 0.155 |
| Th17% | 1.55 (1.10-2.61) | 1.25 (0.80-1.90) | 1.07 (0.67-1.55) | <0.001*** |
| Treg% | 3.78 (2.88-4.75) | 4.47 (3.79-5.86) | 6.43 (5.19-9.62) | <0.001*** |
| Th1/Th2 | 13.03 (8.10-20.80) | 10.32 (6.23-16.88) | 9.24 (5.87-13.35) | 0.006** |
| Th17/Treg | 0.40 (0.30-1.03) | 0.25 (0.17-0.40) | 0.20 (0.11-0.31) | <0.001*** |
Date with median and 25th and 75th percentiles.
T, T lymphocyte; B, B lymphocyte; NK, Natural killer cell; Th1, T-helper 1 cells; Th2, T-helper 2 cells; Th17, T-helper17 cells; Treg, Regulatory T cells. *P<0.05, **P<0.01, ***P<0.001.