TABLE 2.
ELISA units against E. coli- or P. pastoris-derived AMA1-3D7 as a coating antigena
| Immunogen | Rabbit | ELISA units for plate antigen
|
|
|---|---|---|---|
| EcAMA-3D7 | PpAMA-3D7 | ||
| EcAMA1-3D7 (group 3) | 1 | NA | NA |
| 2 | 54,300 | 50,200 | |
| 3 | 101,700 | 98,200 | |
| 4 | 31,880 | 36,700 | |
| 5 | 3,560 | 5,000 | |
| GMb | 28,137 | 30,840 | |
| PpAMA1-3D7 (group 4) | 1 | 22,170 | 27,900 |
| 2 | 29,800 | 42,700 | |
| 3 | 19,850 | 26,000 | |
| 4 | 43,030 | 54,400 | |
| 5 | 208,600 | 159,100 | |
| GMb | 41,131 | 48,490 | |
a
Two groups of five rabbits were each immunized with either E. coli-derived AMA1-3D7 (group 3) or P. pastoris-derived AMA1-3D7 (group 4) three times at 4-week intervals. This table shows ELISA units 2 weeks after the third immunization (day 70). NA, not applicable.
b
GM, Geometric mean.