Skip to main content
. 2025 Jan 1;16(2):622–628. doi: 10.7150/jca.103097

Table 2.

Stratification analysis for the association between NSUN1 gene polymorphisms and neuroblastoma susceptibility

Variables rs11834074
(cases/controls)
AOR (95% CI) a P a rs3764909
(cases/controls)
AOR (95% CI) a P a Protective genotypes
(cases/controls)
AOR (95% CI) a P a
GG GA/AA CC CA/AA 0-1 2
Age, month
≤18 74/71 65/68 0.92 (0.57-1.47) 0.712 62/59 77/80 0.91 (0.57-1.47) 0.710 89/88 50/51 0.97 (0.59-1.58) 0.897
>18 126/153 137/181 0.92 (0.67-1.27) 0.609 113/141 150/193 0.97 (0.70-1.34) 0.853 151/184 112/150 0.91 (0.66-1.26) 0.569
Gender
Females 94/110 97/115 0.99 (0.67-1.46) 0.952 87/94 104/131 0.86 (0.58-1.27) 0.439 111/132 80/93 1.03 (0.69-1.52) 0.902
Males 106/114 105/134 0.84 (0.58-1.22) 0.360 88/106 123/142 1.04 (0.72-1.52) 0.819 129/140 82/108 0.82 (0.57-1.20) 0.308
Sites of origin
Adrenal gland 46/224 47/249 0.91 (0.58-1.42) 0.678 40/200 53/273 0.98 (0.62-1.53) 0.917 57/272 36/201 0.84 (0.53-1.33) 0.448
Retroperitoneal 85/224 82/249 0.87 (0.61-1.24) 0.438 76/200 91/273 0.88 (0.62-1.25) 0.468 101/272 66/201 0.89 (0.62-1.27) 0.510
Mediastinum 56/224 64/249 1.03 (0.69-1.54) 0.897 46/200 74/273 1.18 (0.78-1.78) 0.430 68/272 52/201 1.03 (0.69-1.55) 0.874
Others 10/224 8/249 0.73 (0.28-1.88) 0.510 10/200 8/273 0.58 (0.22-1.49) 0.255 11/272 7/201 0.88 (0.33-2.31) 0.793
Clinical stages
I+II+4s 80/224 93/249 1.04 (0.73-1.48) 0.831 70/200 103/273 1.10 (0.77-1.57) 0.605 102/272 71/201 0.92 (0.65-1.32) 0.664
III+IV 89/224 74/249 0.74 (0.52-1.06) 0.103 78/200 85/273 0.80 (0.56-1.15) 0.228 100/272 63/201 0.84 (0.59-1.22) 0.365

OR, odds ratio; CI, confidence interval.

a Adjusted for age and gender, omitting the correspondence factor.