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In vivo, exosomal miR-552-5p can cause NK cell failure. (A-B) NK cell percentage by flow cytometry; (C-F) NKp46 and NKG2D expression analysis by flow cytometry; (G-I) ELISA detection of the impact of exosomal miR-552-5p derived from gastric cancer cells on the secretion of Granzyme B, Perforin, and IFN-γ in NK cells from the peripheral blood of nude mice (*p < 0.05; **p < 0.01; ***p < 0.001).
