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. 2024 Dec 30;15:10879. doi: 10.1038/s41467-024-55233-7

Fig. 2. TLR2 co-receptors utilisation by vaginal bacteria.

Fig. 2

HEK TLR2 (a) and VK2 vaginal epithelial cells (b) were incubated with bacteria (MOI = 10) overnight. TLR1 and TLR6-dependence was investigated by pre-incubating the cells for 30 min with 1 μg/ml anti-TLR1, anti-TLR6 or mIgG1 isotype control antibodies before overnight stimulation with the bacteria at MOI = 10. Fv Fannyhessea vaginae, Fn Fusobacterium nucleatum, Pb Prevotella bivia, Sv Sneathia vaginalis, Mm Mobiluncum mulieris, Fm Fingoldia magna, Va Veillonella atypica. Data are mean +/−SD (n = 3 biological replicates). Two-way ANOVA, Tuckey multiple comparison test. *p < 0.05, **p < 0.01, ***p < 0.005, ****p < 0001. Source data are provided as a Source Data file.