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. 2024 Dec 30;14:32014. doi: 10.1038/s41598-024-83733-5

Table 2.

The relationship between the prevalence of ED and complete blood cell-derived inflammatory biomarkers.

continuous Quartiles of CBC-derived inflammatory biomarkers levels P trend
OR (95%CI) P value Q1 Q2 Q3 Q4
NLR
Crude 1.27(1.18,1.36) < 0.001 - 0.92(0.67,1.25) 1.23(0.96,1.57) 2.16(1.70,2.73) < 0.001
Model 1 1.09(1.01,1.19) 0.028 - 0.68(0.49,0.95) 0.97(0.71,1.24) 1.17(0.88,1.56) 0.091
Model 2 1.10(1.01,1.20) 0.018 - 0.74(0.52,1.06) 1.03(0.76,1.41) 1.25(0.91,1.71) 0.052
Model 3 1.09(1.00,1.19) 0.021 - 0.75(0.50,1.11) 1.01(0.73,1.39) 1.25(0.91,1.73) 0.061
dNLR
Crude 0.64(0.12,3.42) 0.6 - 0.87(0.69,1.10) 0.76(0.60,0.94) 1.05(0.81,1.38) > 0.9
Model 1 1.11(0.12,10.1) > 0.9 - 0.85(0.63,1.14) 0.70(0.53,0.94) 1.19(0.84,1.70) 0.5
Model 2 1.26(0.09,16.9) 0.9 - 0.89(0.63,1.24) 0.75(0.55,1.03) 1.23(0.82,1.83) 0.5
Model 3 0.92(0.07,12.6) > 0.9 - 0.89(0.61,1.30) 0.74(0.54,1.02) 1.19(0.80,1.79) 0.6
MLR
Crude 13.8(6.88,27.6) < 0.001 - 1.04(0.71,1.50) 1.46(1.09,1.94) 2.32(1.71,3.15) < 0.001
Model 1 2.50(1.04,6.02) 0.032 - 0.80(0.53,1.22) 0.96(0.70,1.32) 1.11(0.75,1.64) 0.4
Model 2 2.94(1.15,7.51) 0.015 - 0.89(0.58,1.38) 1.10(0.77,1.57) 1.24(0.81,1.91) 0.2
Model 3 2.97(1.18,7.50) 0.01 - 0.88(0.54,1.41) 1.12(0.76,1.66) 1.25(0.79,1.97) 0.2
NMLR
Crude 1.26(1.18,1.35) < 0.001 - 0.86(0.66,1.12) 1.17(0.92,1.49) 2.16(1.70,2.75) < 0.001
Model 1 1.09(1.01,1.18) 0.014 - 0.65(0.49,0.86) 0.87(0.67,1.15) 1.15(0.86,1.54) 0.12
Model 2 1.10(1.02,1.19) 0.007 - 0.70(0.53,0.93) 0.96(0.70,1.31) 1.23(0.90,1.69) 0.064
Model 3 1.10(1.01,1.11) 0.006 - 0.71(0.52,0.98) 0.93(0.67,1.28) 1.25(0.90,1.73) 0.073
SIRI
Crude 1.27(1.17,1.39) < 0.001 - 1.07(0.85,1.35) 1.43(1.08,1.88) 2.25(1.85,2.74) < 0.001
Model 1 1.15(1.05,1.26) 0.002 - 0.89(0.69,1.14) 1.05(0.76,1.45) 1.45(1.09,1.93) 0.009
Model 2 1.11(1.01,1.22) 0.019 - 0.88(0.65,1.19) 1.04(0.71,1.51) 1.35(0.98,1.87) 0.055
Model 3 1.11(1.01,1.22) 0.017 - 0.82(0.60,1.13) 1.02(0.67,1.54) 1.28(0.91,1.81) 0.1
SII
Crude 1.00(1.00,1.00) < 0.001 - 0.99(0.76,1.29) 1.06(0.81,1.39) 1.44(1.16,1.80) 0.003
Model 1 1.00(1.00,1.01) 0.2 - 0.92(0.66,1.29) 1.03(0.74,1.43) 1.23(0.89,1.70) 0.14
Model 2 1.00(1.00,1.02) 0.2 - 0.99(0.70,1.42) 1.14(0.81,1.61) 1.28(0.91,1.80) 0.1
Model 3 1.00(1.00,1.03) 0.2 - 0.98(0.68,1.42) 1.18(0.79,1.74) 1.25(0.86,1.82) 0.13

Crude Model: Unadjusted for covariates; Model 1: Adjusted for age and race; Model 2: Adjusted for age, race, marital status, BMI, PIR, education, smoking, alcohol consumption, and physical activity; Model 3: Fully adjusted model including all covariates.