TABLE 3.
Safety of serovar Abortusovis vaccine strains after subcutaneous administration to pregnant ewes
| Straina (group/no. of ewes) | Relevant genotype | No. of abortions | No. of lambs (healthy/deadb) | No. of ewes with infection at parturition |
|---|---|---|---|---|
| SU304 (A/5) | aroA | 0 | 4/1 | 0 |
| SSM189 (B/5) | crp cdt cya | 0 | 5/0 | 0 |
| SU40 (C/5) | Plasmid cured | 0 | 4/1 | 1 |
| SS44 (D/5) | Wild type | 3 | 1/1 | 3 |
a
Serovar Abortusovis wild-type and live vaccine strains were administered at the dose of 1.6 × 109 CFU.
b
Delivered dead lambs had no signs of serovar Abortusovis infection at necropsy.