Peripheral blood levels of chemokines in children with malaria. (A) MIP-1α, (B) MIP-1β, and (C) RANTES levels were determined in plasma of children from the HC (n = 23), MM (n = 10), and SM (n = 10) groups by ELISA. Each box plot represents the range (25th to 75th percentiles) of chemokine concentration for each group, with the median value at the intersect. Statistical significance was determined by Mann-Whitney U test. * denotes P < 0.05 relative to HC; ** denotes P < 0.01 relative to HC.