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Transcriptional profiles of chemokines in children with malaria. Total RNA was isolated from PBMCs obtained from children from the HC (n = 23), MM (n = 10), and SM (n = 10) groups. (A) MIP-1α, (B) MIP-1β, and (C) RANTES gene expression was determined by real time RT-PCR. Data are presented for each chemokine relative to expression of endogenous β-actin. Statistical significance was determined by Mann-Whitney U test. * denotes P < 0.05 relative to HC.
