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. 2024 Dec 16;5:e65506. doi: 10.2196/65506

Table 4.

Pre- and postintervention changes at baseline and end of study period.

Group and parameter Pretest, mean (SD) Posttest, mean (SD) t testa (df) P valueb % change in mean values Effect size (Cohen d)
Intervention group

Perceived Stress Scale score 19.71 (5.09) 16.29 (4.83) 3.661 (33) <.001 –17.35% 0.628

Composite DASS-21c score 21.15 (9.56) 15.41 (7.87) 3.679 (33) <.001 –27.14% 0.631

Depression subcomponent score of the DASS-21 5.35 (3.32) 3.82 (3.19) 2.430 (33) .02 –28.60% 0.417

Anxiety subcomponent score of the DASS-21 6.59 (3.25) 4.71 (2.97) 2.910 (33) .006 –28.53% 0.499

Stress subcomponent score of the DASS-21 8.91 (3.94) 6.47 (3.10) 3.310 (33) .002 –27.38% 0.568

DHEA-Sd levels 251.71 (80.98) 302.74 (123.56) –3.317 (33) .002 20.27% 0.369

IL-6e levels 4.93 (1.35) 3.67 (1.00) 4.089 (33) <.001 –25.56% 0.701
Control group

Perceived Stress Scale score 21.87 (4.64) 20.58 (6.46) 1.040 (30) .31 –6% 0.187

Composite DASS-21 score 22.42 (9.88) 26.13 (9.68) –2.146 (30) .04 17% –0.385

Depression subcomponent score of the DASS-21 6.00 (3.40) 6.77 (4.04) –1.219 (30) .23 13% –0.219

Anxiety subcomponent score of the DASS-21 7.77 (4.20) 9.48 (3.35) –2.394 (30) .02 22% –0.430

Stress subcomponent score of the DASS-21 8.65 (3.73) 9.19 (3.36) –0.724 (30) .47 6% –0.130

DHEA-S levels 285.33 (112.14) 309.90 (136.90) –1.691 (30) .10 9% –0.304

IL-6 levels 4.52 (1.40) 2.72 (1.74) 4.179 (30) <.001 –40% 0.750

aPaired t test, confidence level 95%.

bP<.05/4 was considered statistically significant.

cDASS-21: Depression Anxiety Stress Scale.

dDHEA-S: dehydroepiandrosterone sulfate.

eIL-6: interleukin-6.