Skip to main content
. 2024 Dec 30;14:31605. doi: 10.1038/s41598-024-76981-y

Figure 5.

Figure 5

Effect of necdin deficiency on activation of glial cells. (a, b) Double-labeling for IBA-1 and GFAP in brain sections containing the VTA from 3-month-old mice. Scale bar, 500 μm and 100 μm. The bar plots represent the mean number of IBA-1 or GFAP-positive cells per section in the indicated areas. (c, d) Double-labeling for IBA-1 and GFAP in brain sections containing the VTA from 13-month-old mice. The bar plots represent the mean number of IBA-1 or GFAP-positive cells per section in the indicated areas. (e, f) The mean latency fall over three consecutive days of training on the rotarod in 3 and 13-month-old WT and KO mice. Data were mean ± SEM, n = 4–7 mice/genotype, *p < 0.05, **p < 0.01, unpaired t-test.