TABLE 1.
Immunization groups
| Group (immunization route) | Immunogen | Amt administereda (μg) |
|---|---|---|
| A − Ctb (IN) | Ctb − TbpA conjugate | 20 |
| B − Ctb (IN) | Ctb − TbpB conjugate | 20 |
| A − Ctb + B − Ctb (IN) | Ctb − TbpA + Ctb − TbpB conjugates | 20 + 20 |
| A + Ctb (IN) | Ctb + TbpA admixed | 10 + 10 |
| B + Ctb (IN) | Ctb + TbpB admixed | 10 + 10 |
| A + B + Ctb (IN) | Ctb + TbpA + TbpB admixed | 10 + 10 + 10 |
| A only (IN) | TbpA | 10 |
| B only (IN) | TbpB | 10 |
| Control | PBS only | 0 |
| S.c.A + B + Ctb (s.c.b) | Ctb + TbpA + TbpB admixed | 10 + 10 + 10 |
a
Groups of mice (n = 5) were immunized three times at 10-day intervals.
b
One group was immunized subcutaneously (s.c.) with an admixture of TbpA, TbpB, and Ctb.