TABLE 4.
Serum bactericidal activities of sera collected at day 35
Immunization group | Serum bactericidal titera for strain:
|
||
---|---|---|---|
FA19 | FA1090 | MS11 | |
TbpA − Ctb + TbpB − Ctb | 800 (84 ± 5.7) | 200 (64 ± 1.4) | 400 (60 ± 0.7) |
TbpA − Ctb | 400 (83 ± 4.2) | 25 (<50)b | 200 (64 ± 1.4) |
TbpB − Ctb | 200 (64 ± 1.4) | 25 (<50)b | 50 (56 ± 4.9) |
S.c.d TbpA + TbpB + Ctb | 100 (70 ± 1.4) | 25 (<50)b | 25 (78)b |
TbpA only | 400 (71 ± 9.9) | NDc | ND |
Data are represented as the lowest reciprocal dilution that gave >50% killing. The average percent killing determined from duplicate assays ± standard deviation is shown in parentheses.
Assays conducted at 1/25 dilution were performed only once, and lower dilutions were not tested.
ND, not determined.
S.c., subcutaueous.