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. 2024 Dec 27;16(12):1480–1492. doi: 10.4254/wjh.v16.i12.1480

Table 1.

Serum angiopoietin-2 and hypoxia-inducible factor-1α levels in patients with chronic liver diseases

Group n Ang-2
HIF-1α
mean ± SD (μg/L)
> 35 μg/L, n (%)
mean ± SD (μg/L)
> 100 μg/L, n (%)
HCC 80 42.9 ± 5.1 162 (90.0) 145.6 ± 32.6 163 (90.6)
LC 50 26.2 ± 6.1a 3 (6.0)a 79.5 ± 28.4b 14 (28.0)b
CH 50 21.8 ± 6.9b 2 (4.0)b 60.1 ± 18.8b 1 (2.0)b
NC 50 16.9 ± 2.8b 0 (0.0)b 23.9 ± 4.2b 0 (0.0)b
a

P < 0.05, compared with the hepatocellular carcinoma group.

b

P < 0.01, compared with the hepatocellular carcinoma group.

Ang-2: Angiopoietin-2; HIF-lα: Hypoxia-inducible factor-1α; NC: Normal control; HCC: Hepatocellular carcinoma; LC: Liver cirrhosis; CH: Chronic hepatitis.